Finance

AstraZeneca shares down 3% after rating cut, UK investment pause

Published by Global Banking & Finance Review

Posted on September 15, 2025

2 min read

· Last updated: January 21, 2026

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AstraZeneca shares down 3% after rating cut, UK investment pause
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By Maggie Fick and Danilo Masoni LONDON (Reuters) -AstraZeneca shares fell as much as 3.4% on Monday, their steepest drop since May, after Handelsbanken cut its rating on the drugmaker and Reuters

AstraZeneca Shares Drop 3% Following Rating Downgrade and Investment Halt

Impact of Rating Cut on AstraZeneca

By Maggie Fick and Danilo Masoni

Stock Performance

LONDON (Reuters) -AstraZeneca shares fell as much as 3.4% on Monday, their steepest drop since May, after Handelsbanken cut its rating on the drugmaker and Reuters reported the company had paused a major investment in its home market.

Company Response

The Anglo-Swedish pharmaceutical group's stock underperformed the broader European healthcare index, which was down less than 1% at 11 GMT. Handelsbanken lowered its recommendation on AstraZeneca to "hold" from "buy", citing what it sees as an overly optimistic target of $80 billion in total revenue by 2030.

Investment Plans

Britain's biggest listed company became the latest drugmaker to pull back on its business in the country after it paused a planned 200 million pound ($272.12 million) investment in its Cambridge research centre, a spokesperson told Reuters late on Friday. The move comes as a blow to Prime Minister Keir Starmer's government ahead of U.S. President Donald Trump's state visit to Britain this week.

Shares were down 2.7% at 1100 GMT.

AstraZeneca, which has a robust drug pipeline of blockbuster cancer medicines, did not immediately respond to a request for comment.

($1 = 0.7350 pounds)

(Reporting by Maggie Fick and Danilo Masoni, Editing by Louise Heavens)

Key Takeaways

  • AstraZeneca shares fell 3.4% after a rating downgrade.
  • Handelsbanken changed its rating from 'buy' to 'hold'.
  • AstraZeneca paused a £200 million investment in Cambridge.
  • The stock underperformed the European healthcare index.
  • The investment pause is a setback for the UK government.

Frequently Asked Questions

What caused AstraZeneca's shares to drop?
AstraZeneca shares fell as much as 3.4% after Handelsbanken cut its rating on the drugmaker.
How did AstraZeneca's stock perform compared to the healthcare index?
AstraZeneca's stock underperformed the broader European healthcare index, which was down less than 1%.
What investment decision did AstraZeneca recently make?
AstraZeneca paused a planned 200 million pound investment in its Cambridge research facility.

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