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GSK expects sales, profit toward top of 2025 forecasts despite tariff, pipeline pressures

Published by Global Banking & Finance Review

Posted on July 30, 2025

3 min read

· Last updated: January 22, 2026

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GSK expects sales, profit toward top of 2025 forecasts despite tariff, pipeline pressures
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(Reuters) -British drugmaker GSK said on Wednesday it expects to report annual sales and profit towards the top end of its forecast range, adding that its outlook includes the impact of tariffs in

GSK Aims for Strong Sales and Profit Growth by 2025 Amid Challenges

By Pushkala Aripaka and Maggie Fick

(Reuters) -GSK expects to deliver annual sales and profit growth towards the top end of its forecasts after beating second-quarter expectations on Wednesday, in a boost to its efforts to fuel growth despite product development and tariff challenges.

The British drugmaker is hoping to reach annual sales of over 40 billion pounds ($53.44 billion) by 2031, even as it faces potential pharmaceutical tariffs and drug pricing pressure in the world-leading U.S. market. 

"We're very well positioned and continue to be part of investments so that our portfolio in the U.S. is more and more supplied from the U.S.," CEO Emma Walmsley told journalists.

She added that GSK was also in talks with President Donald Trump's administration, which is pushing drugmakers to cut prices, but offered few details.

The U.S. pharmaceuticals market - worth around $635 billion - makes up slightly over half of GSK's sales and is central to its growth plans.

GSK said it had accounted for levies already implemented by Washington and expected tariffs on Europe's exports under a new U.S.-EU trade deal, as well as possible duties resulting from a U.S. investigation into pharmaceutical imports. 

It expects 2025 revenue to increase between 3% and 5%, with core profit per share growth of 6% to 8% at constant currency rates.

EYES ON DRUG DEVELOPMENT

GSK is focusing on expanding its product pipeline as it faces rising competition and declining sales of top drugs and vaccines. 

It expects five new major approvals this year. 

While second-quarter turnover growth of 6% to nearly 8 billion pounds and earnings of 46.5 pence per share beat analyst estimates, investors are focused on GSK's pipeline as it awaits a final U.S. approval verdict on cancer drug Blenrep.

Analysts say a rejection might force GSK to rethink its 2031 sales target as it is also bracing for patent expirations in its HIV portfolio.

The company's HIV business, as well as specialty medicines, respiratory, and oncology divisions, recorded double-digit revenue growth in the quarter.

But Barclays analysts cautioned HIV sales growth would be slower in the second half due to the timing of stock sales and availability.

GSK expects currency headwinds to be a drag of 4% and 7% on 2025 sales and profit growth, respectively, on a reported basis.

Its shares rose as much as 2% and were trading 1.5% higher at 1127 GMT. 

($1 = 0.7486 pounds)

(Reporting by Pushkala Aripaka in Bengaluru and Maggie Fick in London; Editing by Subhranshu Sahu, Sharon Singleton and Joe Bavier)

Key Takeaways

  • GSK aims for top-end sales and profit growth by 2025.
  • Facing tariff and drug pricing challenges in the U.S.
  • Plans to expand product pipeline with major approvals.
  • HIV and specialty medicines show strong revenue growth.
  • Currency headwinds expected to impact sales and profit.

Frequently Asked Questions

What is GSK's sales target for 2031?
GSK aims to achieve annual sales of over 40 billion pounds ($53.44 billion) by 2031.
How does GSK plan to address drug pricing pressures?
GSK is in talks with the U.S. administration, which is pushing drugmakers to cut prices, although few details were provided.
What is the expected revenue growth for GSK by 2025?
GSK expects its revenue to increase between 3% and 5% by 2025, with core profit per share growth of 6% to 8% at constant currency rates.
What challenges does GSK face in its product pipeline?
GSK is facing rising competition and declining sales of top drugs and vaccines, prompting a focus on expanding its product pipeline.
How are currency fluctuations expected to affect GSK's growth?
GSK anticipates currency headwinds to negatively impact sales and profit growth by 4% and 7%, respectively, on a reported basis.

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