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Novo Nordisk plans to start late-stage trials of obesity drug amycretin next year

Published by Global Banking & Finance Review

Posted on June 12, 2025

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· Last updated: January 23, 2026

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Novo Nordisk plans to start late-stage trials of obesity drug amycretin next year
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(Reuters) -Novo Nordisk said on Thursday it plans to start late-stage trials of amycretin injection and oral drugs during the first quarter of 2026 for adults who are overweight or obese. (Reporting

Novo Nordisk to Initiate Late-Stage Trials for Obesity Drug Amycretin

(Reuters) -Novo Nordisk said on Thursday it plans to start late-stage trials of its experimental weight-loss drug amycretin in injection and oral forms during the first quarter of 2026 for adults who are overweight or obese.

The decision to advance the trials is based on feedback received from regulatory authorities in interactions following the end of its mid-stage trials, the company said.

Amycretin, the Danish drugmaker's next generation obesity drug, has a dual mode action. Like its popular weight-loss drug Wegovy, amycretin mimics the gut hormone GLP-1, but it also mimics the effect of a hunger-suppressing pancreatic hormone called amylin.

(Reporting by Harshita Meenaktshi and Sriparna Roy in Bengaluru; Editing by Leroy Leo)

Key Takeaways

  • Novo Nordisk plans late-stage trials for amycretin in 2026.
  • Amycretin targets overweight and obese adults.
  • The drug mimics GLP-1 and amylin hormones.
  • Feedback from regulatory authorities influenced the trial decision.
  • Amycretin is available in injection and oral forms.

Frequently Asked Questions

When does Novo Nordisk plan to start late-stage trials for amycretin?
Novo Nordisk plans to start late-stage trials of amycretin in the first quarter of 2026.
What prompted Novo Nordisk to advance the trials for amycretin?
The decision to advance the trials is based on feedback received from regulatory authorities following the end of its mid-stage trials.
How does amycretin work as an obesity drug?
Amycretin mimics the gut hormone GLP-1 and has a dual mode of action, similar to Novo Nordisk's popular weight-loss drug Wegovy.

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