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Zealand Pharma may sell future obesity drug direct to patients

Published by Global Banking & Finance Review

Posted on September 22, 2025

2 min read

· Last updated: January 21, 2026

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LONDON (Reuters) -Zealand Pharma is considering a direct-to-patient sales model for its experimental weight-loss drug alongside traditional insurer channels, its CEO told Reuters in an interview on

Zealand Pharma may sell future obesity drug direct to patients

Direct-to-Patient Sales Strategy

LONDON (Reuters) -Zealand Pharma is considering a direct-to-patient sales model for the experimental weight-loss drug it is developing with Roche alongside traditional insurer channels, its CEO told Reuters on Monday.

Clinical Trial Timeline

The company is expecting results from its mid-stage clinical trial of the drug, petrelintide, in the first half of 2026, and plans to begin a late-stage trial in the second half. It announced an up to $5.3 billion deal with Roche to co-develop the drug in March.

Market Evolution and Strategy

In an interview, Zealand CEO Adam Steensberg said the company is mulling a direct-to-consumer strategy from the outset because of how the market has evolved since Novo Nordisk and Eli Lilly launched their GLP-1 therapies from 2021 onwards.

Consumer Engagement in Obesity Treatment

After encountering patient access hurdles and struggling to secure broad insurance coverage in the U.S., both drugmakers later launched direct-to-consumer online platforms. "We expect this (direct-to-consumer) market will continue to grow," Steensberg said.

Zealand's experimental drug is based on a different hormone, amylin, which has shown in early clinical trials to cause less severe and frequent gastrointestinal side effects than the GLP-1 injections.

Obesity drugs lend themselves to chronic therapy and consumer-style engagement, much like buying a product you use long-term, Steensberg said.

He said the model still requires a prescription, so it is not over-the-counter, but would be delivered via telehealth or virtual clinics, as is the case currently with Novo's Wegovy injection and Lilly's Zepbound.

(Reporting by Maggie Fick; Editing by Jan Harvey)

Key Takeaways

  • Zealand Pharma is exploring direct-to-patient sales for its obesity drug.
  • The drug, petrelintide, is being co-developed with Roche.
  • Clinical trial results are expected in the first half of 2026.
  • The strategy is influenced by market changes from GLP-1 therapies.
  • The drug aims to reduce gastrointestinal side effects.

Frequently Asked Questions

What is Zealand Pharma's new sales model for its obesity drug?
Zealand Pharma is considering a direct-to-patient sales model for its experimental weight-loss drug, petrelintide, alongside traditional insurer channels.
When are the clinical trial results expected for petrelintide?
The company expects results from its mid-stage clinical trial of petrelintide in the first half of 2026.
How does Zealand Pharma's drug differ from existing obesity treatments?
Zealand's experimental drug is based on a different hormone, amylin, which has shown in early trials to cause fewer gastrointestinal side effects compared to GLP-1 injections.
What challenges did Novo Nordisk and Eli Lilly face in the U.S. market?
Both companies encountered patient access hurdles and struggled to secure broad insurance coverage, leading them to launch direct-to-consumer online platforms.
Will Zealand Pharma's drug be available over-the-counter?
No, the model still requires a prescription, but it would be delivered via telehealth or virtual clinics.

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