Finance

Novo Nordisk flags near-term headwinds in international operations

Published by Global Banking & Finance Review

Posted on January 13, 2026

2 min read

· Last updated: January 19, 2026

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Jan 13 (Reuters) - Novo Nordisk CEO Mike Doustdar said on Tuesday the drugmaker expects headwinds in its international operations in 2026, as competition intensifies after losing market exclusivity in

Novo Nordisk Anticipates Challenges in Global Operations for 2026

Challenges in International Operations

Jan 13 (Reuters) - Novo Nordisk CEO Mike Doustdar said on Tuesday the drugmaker expects headwinds in its international operations in 2026, as competition intensifies after losing market exclusivity in several countries.

CEO's Insights on Market Competition

Speaking at the J.P. Morgan Healthcare Conference, Doustdar said international markets represent the company's biggest long-term volume opportunity for its weight-loss and diabetes franchise, but acknowledged near-term pressure as rivals enter markets where Novo has historically held high market share.

Concerns Over Wegovy Pill Requirements

"When you have a very high market share, competition will take some of that share away," he said, adding that the company could face "a difficult year" due to expiry of exclusivity in parts of its international portfolio.

Comparative Analysis with Eli Lilly

Doustdar said Novo, which operates in around 80 to 85 markets through local affiliates, remains structurally well positioned outside the United States, but must adapt to a changing obesity market where cross-border and online sales are easier.

He also pointed to growing competition from Eli Lilly in several international geographies, saying Novo would rely on capacity expansion, higher-dose formulations and new products to defend its position.

CEO PLAYS DOWN FASTING REQUIREMENT CONCERNS FOR WEGOVY PILL

Addressing concerns around fasting requirements for its recently approved weight-loss pill version of Wegovy, Doustdar said Novo has not seen evidence that such restrictions are a barrier, pointing to around 1.5 million patients using Rybelsus, its oral semaglutide for patients with type 2 diabetes.

Novo's oral semaglutide needs to be taken in the morning on an empty stomach, 30 minutes before eating, drinking or using any other oral medication. Rival Lilly's experimental pill orforglipron does not have those restrictions.

Analysts have said that the lack of dietary restrictions could give Lilly an edge.

Doustdar noted that trial protocols for Lilly's orforglipron show some patients taking certain statins, or cholesterol-busting drugs, may need to wait two to four hours before dosing.

(Reporting by Mrinalika Roy in Bengaluru; Editing by Alan Barona)

Key Takeaways

  • Novo Nordisk expects challenges in 2026 due to market exclusivity loss.
  • CEO highlights competition from Eli Lilly in international markets.
  • Company aims to defend its position with new products and strategies.
  • Concerns over Wegovy pill's fasting requirements are addressed.
  • International markets are seen as long-term volume opportunities.

Frequently Asked Questions

What is market exclusivity?
Market exclusivity refers to the period during which a company has exclusive rights to sell a product, preventing competitors from entering the market with similar products.
What is a strategic adaptation?
Strategic adaptation involves changing business strategies to respond to market conditions, competition, or consumer preferences to maintain or improve a company's position.

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