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UK’s FTSE 100 falls as AstraZeneca, BoE Governor’s remarks weigh

Published by Jessica Weisman-Pitts

Posted on December 4, 2024

2 min read

· Last updated: January 28, 2026

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Decline of UK’s FTSE 100 influenced by AstraZeneca and Bank of England remarks - Global Banking & Finance Review
This image depicts the financial market trends of the UK's FTSE 100 index, highlighting the impact of AstraZeneca's stock decline and Bank of England's Governor remarks on interest rates, crucial for investors.
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(Reuters) – The UK’s benchmark FTSE 100 fell on Wednesday, ending a five-day winning streak, dragged by AstraZeneca’s decline on target price cut, while investors assessed domestic economic data and Bank of England Governor’s Andrew Bailey remarks on interest rate cuts. The blue-chip FTSE 100 fell 0.3%, while the midcap FTSE 250 rose 0.2% to […]

(Reuters) – The UK’s benchmark FTSE 100 fell on Wednesday, ending a five-day winning streak, dragged by AstraZeneca’s decline on target price cut, while investors assessed domestic economic data and Bank of England Governor’s Andrew Bailey remarks on interest rate cuts.

The blue-chip FTSE 100 fell 0.3%, while the midcap FTSE 250 rose 0.2% to hit more than a six-week high at 1012 GMT.

AstraZeneca slipped 2.7% to the bottom of the blue-chip index after HSBC analysts cut the target price on the drugmaker’s stock to 13,720p from 14,070p.

BoE’s Bailey reiterated that there will be gradual cuts in interest rates next year, adding that the process of falling inflation is well embedded.

The BoE is expected to keep interest rates on hold at 4.75% this month, but deliver about 78 basis points worth of rate cut by the end of next year.

The sterling fell after the Financial Times reported Bailey saying the BoE expected four interest rate cuts next year.

Shares of miners Antofagasta, Glencore and Anglo American declined between 0.9% and 1.7% with copper prices easing against a firm dollar. [MET/L]

Additionally, ZIGUP was the top loser on the midcap index, falling 8.4% as the commercial vehicle rental provider’s pretax profit fell 17.2% to 82 million pounds ($104.1 million) for the first half.

Legal & General was a standout and gained 3.4% as the life insurer said it anticipates returning to shareholders a proportion of capital this year and was on track to deliver mid-single digit growth in operating profit for the financial year 2024.

Meanwhile, Britain’s dominant services sector lost steam in November, although not as much as first feared, as a looming rise in employer taxes weighed on firms’ hiring plans, a survey showed.

On the global front, investors braced for a crucial no-confidence vote by French lawmakers that will likely oust Prime Minister Michel Barnier’s government. France’s benchmark index CAC 40 was up 0.2%.

(This story has been corrected to say ‘six-week high,’ not ‘seven-week high,’ in paragraph 2)

(Reporting by Nikhil Sharma in Bengaluru; Editing by Shinjini Ganguli)

Frequently Asked Questions

What is the FTSE 100?
The FTSE 100 is a stock market index that represents the 100 largest companies listed on the London Stock Exchange, reflecting their market capitalization.
What are interest rates?
Interest rates are the cost of borrowing money or the return on savings, expressed as a percentage of the amount borrowed or saved.
What is the Bank of England?
The Bank of England is the central bank of the United Kingdom, responsible for issuing currency, managing monetary policy, and ensuring financial stability.
What is inflation?
Inflation is the rate at which the general level of prices for goods and services rises, eroding purchasing power.
What is a target price in stock trading?
A target price is a projected price level that an analyst believes a stock will reach within a certain timeframe, often used to guide investment decisions.

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